THE RELATIONSHIP BETWEEN MALOCCLUSION AND CRANIOFACIAL PROFILE PATHOLOGY
DOI:
https://doi.org/10.21272/eumj.2025;13(1):274-284Keywords:
Cone-beam computer tomography, dentofacial abnormality, incidental findings; paranasal sinus, skeletal class, facial patternAbstract
Introduction. In orthodontic patients often together with malocclusion there are disorders of the craniofacial structures that make orthodontic treatment difficult. Many accompanying pathologies that can be detected on Cone Beam Computed Tomography of the skull by accident and defined as findings, which are not related to the clinical indications for conducting this study, but may affect the result of orthodontic treatment.
The purpose of this study was to identify the incidental findings of no interest to the orthodontist in the pathology of the craniofacial profile and cervical spine during the analysis of the CBCT of the skull and to evaluate their frequency and relationship with malocclusion in the sagittal, vertical and transverse planes.
Materials and methods. A total of 280 patients with malocclusion were studied with CBCT. An X-ray evaluation of the CBCT of the craniofacial profile was carried out for pathological changes or anomalies in the development of anatomical structures of the skull. The cephalometric characteristics of the sagittal and vertical skeletal pattern were carried out according to Steiner, Transverse skeletal pattern was carried out according to Ricketts.
Results. The most common pathology in patients with malocclusion is the curvature of the nasal septum in 61.4%. Cysts of the maxillary sinuses were observed in 31.1% of cases, thickening of the mucous membrane of the maxillary sinuses in 25% of cases. A statistically significant relationship of hypoplasia of the maxillary sinuses with skeletal class III and hyperdivergent growth type was established.
Conclusions. CBCT provides basic information for further necessary studies of related pathologies. Correct identification of these findings will reduce further diagnostic errors and allow choosing an appropriate treatment plan based on a multidisciplinary approach.
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George AM, Felicita AS, Milling Tania SD, Priyadharsini JV. Systematic review on the genetic factors associated with skeletal Class II malocclusion. Indian J Dent Res. 2021;32(3):399-406. https://doi.org/10.4103/ijdr.IJDR_59_20
Vyzhenko YeYe, Kuroiedova VD, Korobov PS, Halych LB. The influence of chronic stress on periodontal tissues in orthodontic patients in conditions of martial law. Medicni perspektivi. 2024;29(1):127-134. https://doi.org/10.26641/2307-0404.2024.1.300783
Lombardo G, Vena F, Negri P, Pagano S, Barilotti C, Paglia L, et al. Worldwide prevalence of malocclusion in the different stages of dentition: A systematic review and meta-analysis. Eur J Paediatr Dent. 2020;21(2):115–22. https://doi.org/10.23804/ejpd.2020.21.02.05
Sokologorska-Nykina YuK, Kuroiedova VD, Stasiuk OA, Korobov PS. Electromygraphic Potential of Mastication Muscles of Patients with Hearing Deprivation and Dental Anomalies. Journal of International Dental &Medical Research. 2024; 17.1: 239-246.
Smaglyuk LV, Voronkova HV, Karasiunok AY, Liakhovska AV, Solovei KO. Interdisciplinary approach to diagnostics of malocclusions (review). Wiadomosci lekarskie. 2019;72(5 cz 1):918–922.
Liakhovska TYu, Hromova AM, Ketova OM, Smagliuk LV, Liakhovska AV. Features of physical and sexual development and the state of bone tissue in adolescent girls. Ukrainian Journal of Perinatology and Pediatrics. 2023:96(4):91–99.
Skrypnyk M, Petrushanko T, Neporada K, Petrushanko V, Skrypnyk I. Changes in the periodontium against the background of systemic vascular reactions in young individuals with obesity. Dent Med Probl. 2024;61(2):197-207. https://doi: 10.17219/dmp/157294.
Chen W, Zeng H, Wang X, Xu Q, Liu P, Zhang L, et al. A structural equation modeling approach to determine the correlation between the vertical and sagittal skeletal patterns and posterior basal bones mismatching in patients with skeletal Class III malocclusion. Am J Orthod Dentofacial Orthop. 2022;162(6):e277–94. https://doi.org/10.1016/j.ajodo.2022.08.015
Tian Y, Mao B, Cui S, Guo Y, Zhao N, Zhang Y, et al. Effects of orthodontic camouflage treatment vs orthodontic-orthognathic surgical treatment on condylar stability in Class II hyperdivergent patients with severe temporomandibular joint osteoarthrosis: a retrospective observational study. Angle Orthod. 2023;93(4):458–66. https://doi.org/10.2319/090622-622.1
Abdelkarim A. Cone-Beam Computed Tomography in Orthodontics. Dent J (Basel). 2019;7(3):89. https://doi:10.3390/dj7030089
Korobeinikova YuL, Korobeinikov LS. Cone-Beam Computed Tomography in Dental Practice: Literature Review and Own Observations. Journal of International Dental and Medical Research. 2023;16(4):1747- 1752.
Stasiuk AA, Vyzhenko YY, Makarova AN, Kuroiedova VD, Sokolohorska-Nykina YK. The evaluation of heads of temporomandibular joint (TMJ) position in patients with malocclusion. New Armenian Medical Journal. 2020;14(1):48-53.
Avsever H, Gunduz K, Karakoç O, Akyol M, Orhan K. Incidental findings on cone-beam computed tomographic images: paranasal sinus findings and nasal septum variations. Oral radiology. 2018;34(1):40–8. https://doi: 10.1007/s11282-017-0283-y
Ali AHA, Serhan OO, Alsharif MHK, et al. Incidental detection of paranasal sinuses abnormalities on CT imaging of the head in Saudi adult population. PLoS One. 2022;17(9):e0270764. https://doi:10.1371/journal.pone.0270764
Akay G, Yaman D, Karadağ Ö, Güngör K. Evaluation of the Relationship of Dimensions of Maxillary Sinus Drainage System with Anatomical Variations and Sinusopathy: Cone-Beam Computed Tomography Findings. Med Princ Pract. 2020;29(4):354-363. https://doi: 10.1159/000504963
de Carvalho AB, Ferreira Costa AL, Fuziy A, de Assis AC, Castro Veloso JR, Coutinho Manhães LR, et al. Investigation on the relationship of dimensions of the maxillary sinus drainage system with the presence of sinusopathies: a cone beam computed tomography study. Arch Oral Biol. 2018;94:78–83. https://doi.org/10.1016/j.archoralbio.2018.06.021
Gruszka K, Aksoy S, Różyło-Kalinowska I, Gülbeş MM, Kalinowski P, Orhan K. A comparative study of paranasal sinus and nasal cavity anatomic variations between the Polish and Turkish Cypriot Population with CBCT. Head Face Med. 2022;18:37.
Festa P, Mansi N, Varricchio AM, Savoia F, Calì C, Marraudino C, et al. Association between upper airway obstruction and malocclusion in mouth-breathing children. Acta Otorhinolaryngol Ital. 2021;41(5):436–42. https://doi.org/10.1186/s13005-022-00340-3
Hasanin M, El-Naghy R, Olson D, Al-Jewair T. Three-dimensional analysis of upper airway and craniofacial morphology in orthodontic adolescents with Attention Deficit Hyperactivity Disorder (ADHD): A comparative retrospective study. Int Orthod. 2021;19(4):622–32. https://doi.org/10.1016/j.ortho.2021.08.005
Nowak M, Golec J, Wieczorek A, Golec P. Is There a Correlation between Dental Occlusion, Postural Stability and Selected Gait Parameters in Adults? Int J Environ Res Public Health. 2023;20(2):1652. https://doi.org/10.3390/ijerph20021652
Smaglyuk , Karasiunok A, Kulish N, Liakhovska A, Voronkova H, Bilous A, Smaglyuk V. Optimization of the clinical diagnostic examination algorithm of patients with a cross bite complicated by cranio-mandibular dysfunction and postural disorder. Pol Merkur Lekarski. 2024;52(2):203-207. doi: 10.36740/Merkur202402109. https://doi.org/10.36740/Merkur202402109
Kuroiedova VD, Vyzhenko EE, Makarova OM, Stasiuk O.A. Scientific justification of the use of cone-beam computerized tomography (cbct) for cephalometric analysis in the «Аudaxceph» programm. Ukrainian Dental Almanac. 2019;4:52–56.
Amer NM, Aboalnaga AA, Salah Fayed MM, Labib AH. Transverse Malocclusion and Temporomandibular Disorders: Verification of the Controversy. J Oral Facial Pain Headache. 2019;33(4):355–61. https://doi.org/10.11607/ofph.2286
The jamovi project (2022). jamovi. (Version 2.3) [Computer Software]. Retrieved from https://www.jamovi.org
Kose SK, Aksoy S, Onder M, Oz U, Orhan K. Association among Orthodontic Malocclusions, Paranasal Sinuses Anatomic Variations and Adenoid Vegetation in Children Using CBCT. Children (Basel). 2023;10(9):1549. https://doi.org/10.3390/children10091549
Ata-Ali J, Diago-Vilalta JV, Melo M, Bagán L, Soldini MC, Di-Nardo C, Ata-Ali F, Mañes-Ferrer JF. What is the frequency of anatomical variations and pathological findings in maxillary sinuses among patients subjected to maxillofacial cone beam computed tomography? A systematic review. Med Oral Patol Oral Cir Bucal. 2017;22(4):e400-e409. https://doi.org/10.4317/medoral.21456
Occasi F, Perri L, Saccucci M, Di Carlo G, Ierardo G, Luzzi V, De Castro G, Brindisi G, Loffredo L, Duse M, et al. Malocclusion and rhinitis in children: An easygoing relationship or a yet to be resolved paradox? A systematic literature revision. Ital. J. Pediatr. 2018;44:100. https://doi.org/10.1186/s13052-018-0537-2
Abate A, Gaffuri F, Lanteri V, Fama A, Ugolini A, Mannina L, et al. A CBCT based analysis of the correlation between volumetric morphology of the frontal sinuses and the facial growth pattern in caucasian subjects. A cross-sectional study. Head Face Med. 2022;18(1):4. https://doi.org/10.1186/s13005-022-00308-3
Lin L, Zhao T, Qin D, Hua F, He H. The impact of mouth breathing on dentofacial development: A concise review. Front Public Health. 2022;10:929165. https://doi.org/10.3389/fpubh.2022.929165
Florez BM, Tagawa DT, Inoue DP, Yamashita HK, Aidar LA de A, Dominguez GC. Associations between skeletal discrepancies, breathing pattern, and upper airway obstruction in Class III malocclusions. Int J Pediatr Otorhinolaryngol. 2023;166:111471. https://doi.org/10.1016/j.ijporl.2023.111471
Cheng B, Mohamed AS, Habumugisha J, Guo Y, Zou R, Wang F. A Study of the Facial Soft Tissue Morphology in Nasal- and Mouth-Breathing Patients. Int Dent J. 2023;73(3):403–9. https://doi.org/10.1016/j.identj.2022.09.002
Lan Y, Chen J, Chen S, He Y, Huang F. Influences of Adenoid Hypertrophy on Children’s Maxillofacial Development. Healthcare (Basel). 2023;11(21):2812. https://doi.org/10.3390/healthcare11212812
Sandoval C, Díaz A, Manríquez G. Assessing cervical spine and craniofacial morphology in Class II and Class III malocclusions: A geometric morphometric approach. Cranio. 2024 Jul;42(4):450–60. https://doi.org/10.1080/08869634.2021.1987040
Adisen SR, Adisen MZ, Ozdiler FE. The evaluation of the relationship between cervical vertebral anomalies with skeletal malocclusion types and upper airway dimensions. Cranio. 2020;38(3):149–57. https://doi.org/10.1080/08869634.2018.1503136
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Copyright (c) 2025 Yevhenii Vyzhenko, Vira Kuroiedova, Hanna Vyzhenko, Oleksandra Makarova, Oleksii Stasiuk, Liudmyla Halych
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