OSTEOPOROSIS AND SARCOPENIA: COMMON ETIOPATHOGENETIC FACTORS, PREVENTION AND NON-DRUG TREATMENT
DOI:
https://doi.org/10.21272/eumj.2020;8(4):466-474Keywords:
osteosarcopenia, osteosarcopenic obesity, prevention, disorders of fat metabolismAbstract
Introduction. The problem of osteoporosis and sarcopenia is one of the leading problems in world medicine. There is a significant increase in the number of patients with these pathologies, which is associated with increased life expectancy. Osteoporosis and sarcopenia are among the most common diseases in old age. Moreover, if earlier these pathologies, especially osteoporosis, were observed mainly in the elderly, now these diagnoses have significantly rejuvenated. Thus, early diagnosis, methods of prevention, early treatment and rehabilitation of these diseases become relevant. Equally important is the relationship between these diseases and the commonality of their etiology and pathogenesis, and, accordingly, the identity of methods of prevention and treatment.
Purpose. Based on the analysis of theoretical aspects to identify the most susceptible to these pathologies of the population, to study and implement methods of early prevention and non-drug treatment of osteoporosis and sarcopenia.
Methods. Theoretical analysis of literature sources and results of modern research presented in electronic scientific publications included in scientometric databases PubMed, Index Copernicus, Ulrich's Periodicals, Google Scholar, Web of Science, Scopus, Medline and others.
Results. In the context of medical and preventive care, the commonalities and differences of genetic, biochemical and age factors and nosological units that lead to the development of these pathologies are analyzed. Methods of prevention and non-drug treatment of osteoporosis and sarcopenia are considered in detail. The most effective methods of prevention and non-drug treatment of osteoporosis and sarcopenia have been identified.
Conclusions. The common etiopathogenetic factors of sarcopenia and osteoporosis, disorders of fat metabolism and, ultimately, reduced physical activity, suggests the presence of osteosarcopenia and osteosarcopenic obesity. The same commonality leads to almost identical approaches in the treatment and prevention of these diseases
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Copyright (c) 2020 V. A. Malakhov, A. K. Tyagniryadko, Y. A. Isaeva
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