The issue of diagnostics, treatment and social rehabilitation of patients with endogenous psychoses with episodic course remains one of the most urgent problems of psychiatry, which, despite the considerable advances of science and practice, has not found a definitive solution. Significant difficulties of nosological separation in the group of endogenous psychoses with episodic course and evaluation of the pathopersonological aspect of the clinic are related to schizoaffective disorder.
The aim of the study was to establish a typology of pathopersonological transformations in patients with schizoaffective disorder based on the analysis of clinical-psychopathological, medical-psychological, clinical-ethological characteristics of remission. On the basis of “Regional Clinical Psychiatric Hospital” (Zaporizhzhіa) 102 persons with the established diagnosis of schizoaffective disorder were examined. The main methods of the study were clinical psycho-pathological, psychodiagnostic, patho-psychological, clinical-anamnestic, clinical-medical, social-medical and statistical analysis.
As a result of the conducted research, on the basis of the analysis of clinical-psychopathological, medical-psychological, clinical-ethological characteristics of remission, the typology of pathopersonological transformations was established.
The presence and prevalence of 4 main types of pathopersonological transformations in schizoaffective disorder (“affective-labile” (20.1 % of the contingent), “paranoid-dysthymic” (17.3 %), “hysteroid-agonistic” (25.9 %), “Neurocognitive-deficient” (16.9 %) and “mixed” (19.8 % of the contingent)), which differ in clinical-anamnestic, clinical-psychopathological, medical-psychological, neuropsychological and clinical-ethological characteristics and cause social (labor and family) maladjustment of varying degrees.
The clinical-anamnestic, clinical-psychopathological, medical-psychological, neuropsychological and clinical-ethological features identified in the study can be used to determine the type of pathopersonological transformations and its severity in patients with schizoaffective disorder and, accordingly, quantitative characteristics of individually needed psychopharmacological, psychotherapeutic and social rehabilitation activities and evaluation of their effectiveness in dynamics.
2. Wilson JE, Nian H, & Heckers S. The schizoaffective disorder diagnosis: a conundrum in the clinical setting. European Archives Psychiatry and Clinical Neuroscience. 2014; 264(1), 29–34. doi: 10.1007/s00406-013-0410-7
3. Chugunov VV, Kireeva, EN Mediko-psikhologicheskie prediktory prodromal’nogo perioda povtornogo epizoda rekurrentnogo depressivnogo rasstrojstva [Medical and psychological predictors of prodromal period of repeated episode of major depressive disorder]. Zaporozhye medical journal. 2014; 3, 71–76. [in Russian]. doi: https://doi.org/10.14739/2310-1210.2014.3.26035
4. Kay SR, Fiszbein A & Opler LA. (1987) The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophrenia Bulletin (Oxford), 13(2), 261–276. DOI: 10.1093/schbul/13.2.261
5. Vasserman LI, Dorofeeva SA, Meerson YaA Metody neiropsikhologicheskoi diagnostiki. Prakticheskoe rukovodstvo [Methods of neuropsychological diagnosis. A Practical Guide]. Saint-Petersburg: Stroilespechat' Publ, 1997. 198 p.
6. Vasserman LI, Iovlev BV, Karpova EB, Vuks AYa Psikhologicheskaya diagnostika otnosheniya k bolezni: Posobie dlya vrachei [Psychological assessment of attitude toward disease]. St.Petersburg.: Bekhterev Psychoneurological Research Institute, 2005. 32 p.
7. Sobchik LN. Standartizirovannyy mnogofaktornyy metod issledovaniya lichnosti SMIL. [Standardized multifactorial method of studying personality SMIL]. SPb.: Rech' Publ., 2000. – 219 p. ISBN 5-9268-0033-1.
8. Samokhvalov VP, & Samokhvalova OE. Toward a Neuroethology of Schizophrenia: Findings from the Crimean Project. Handbook of Schizophrenia Spectrum Disorders, 2, 2011. pp. 121–164. doi: 10.1007/978-94-007-0831-0_6
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